Considering the development dilemma of general Chinese science and technology journals faced, and combining with the development trends of Chinese journals in new era, the reforming of Science and Technology of Cereals, Oils and Foods was taken as an example to introduce its route of exploring featuresaccording to itself situation. At first, we needed to raise the political standing, and deeply understood President Xi Jinping’s important instruction guide spirit about Chinese science and technology journals, and the main direction and practice of national policy files related to journal development. Second, it’s important to grasp the ideology, and strengthen the political, mission and innovation consciousness. It is necessary to find the journal’s correct positioning, and firmly hold the journal position of the correct public opinion orientation. Third, it’s key to use consciousness guide action, integrate political theory into reforming practices, and combine layout and idea into supporting measures. As a result, the reforming practices generated unique internationalization, special column and visual features of the journal and largely improved academic and industry influences, due to the condition support from internal and external circumstances. Finally, it is discussed that Chinese science and technology journals should discard “examination-oriented education”, pursue all-around development of “quality education”, and strive to achieve self-reliance and self-improvement, with a firm cultural confidence to take the road of characteristic development. This paper is for displaying a trial of a kind of thought and route to run the journal, and for providing a reference case to assist construction of strong nation for Chinese science and technology journal.