Abstract:This study establishes an analytical method for simultaneous determination of 19 Succinate dehydrogenase inhibitor fungicides pesticide residues in Green coffee by QuEChERS-Liquid chromatography tandem mass spectrometry. The Green coffee powder samples were extracted with acetonitrile by Homogenizer, the supernatant were purified by Magnesium sulfate anhydrous、PSA and C18, liquid chromatograhy - tandem mass spectrometry were used for analyzing 19 Succinate dehydrogenase inhibitor fungicides pesticide residues at positive ion mode. The results showed that the calibration curves of 19 targets showed good linearity with correlation coefficients of above 0.995 0 in the range of 1~100 ng/mL, the recoveries of 19 pesticides were 79.6%~109.4% and the relative standard deviations(RSD, n=6) were in the range of 1.4%~9.7% at spiked levels of 0.01、0.05 and 0.1 mg/kg. Limit of quantitation (LOQ) of all the tested pesticides were 0.51~4.60 μg/kg. This method has good linear relations, excellent stable and sensitive, accuracy and precision meet the requirement of quantitative analysis, it is suitable for quantitative analysis of 19 Succinate dehydrogenase inhibitor fungicides pesticide residues in Green coffee.