Phosphine and sulfuryl fluoride are two kinds of fumigation insecticides allowed for use in China and overseas. Phosphine is the “trump card” fumigation insecticide for stored grain, while Sulfuryl fluoride is mainly used as the phosphine resistance management drug. Therefore, both of them are complementary to a certain extent. In view of the application status, problems, and challenges faced by the prevention and control of stored grain pests in China, this paper investigated and sorted out the basic technical characteristics, main production enterprises, production and sales, application technology, residual problems, disposal methods, and application dominance of global grain fumigation pesticide aluminum phosphide (phosphine). Combined with the domestic and international situation, this paper also summarized the technical characteristics, its relationship with phosphine, demand, application characteristics and existing problems of sulfuryl fluoride fumigation, and put forward the suggestions and necessity of systematically carrying out the research on sulfuryl fluoride fumigation and its impact on the environment, so as to comply with the concept of “green, ecological, economic and efficient” and provide reference for the scientific and technological development of stored grain pest control in China.