Taking the black sesame compound honey pill as the research object, the acid value and peroxide value are used as evaluation indicators to investigate the influence of different storage temperatures on its quality; on this basis, the shelf life of the black sesame compound honey pill under naked packaging conditions is predicted by constructing an Arrhenius model. In order to further extend the shelf life, four different packaging forms were set up to package the black sesame compound honey pill, and the effects of different packaging methods on its storage quality such as moisture, texture, and physical and chemical properties were investigated at the same time. The results showed that: compared with the control group, nitrogen filling, shelling and wax sealing have a certain effect on preventing the black sesame compound honey pill from decreasing moisture and increasing hardness and acid value. The packaging form of wax paper + pill shell + wax seal + tin foil paper + polyethylene plastic bag has the best effect. The research results provide a reference for the storage of honey pill products.