This study is to elucidate the prevalence of multi-component mycotoxins in maize from clients in 2020 by high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). The maize samples in this study were prevalence of masked mycotoxins and emerging toxins. For the masked-Mycotoxins, most of samples were failed to be tested out. The D3G & 15-ACDON in some samples are the most prevalence which are at the level of 92.3% and 64.4%, for the emerging Mycotoxins, the beauvericin and moniliform in a few of samples are the most prevalence that are at the level of 96.69% and 95.03%. Through the analysis of these data, this paper aims to provide reference and guidance for the control of masked mycotoxin and emerging toxin.