In view of the mycotoxin pollution in China, a set of methods that are suitable to carry out food safety risk surveillance in China were explored during the 13th Five-year Plan period. The technic used is based on the simultaneous detection of multiple toxins, covering a variety of key foods. The purpose was to gain an overview of the current pollution as comprehensive as possible. It has been proved that the current approach achieved good results and laid a solid foundation for a more comprehensive monitoring in the 14th Five-year plan.