In order to effectively resolve the conflicts between environmental protection, output and benefit during grain cleaning, the vibration screening, specific gravity air separation, cyclone separation, pulse dust removal, closed-loop air circulation and other dust removal technologies are integrated. Efficient dust-free cleaning screens are developed. To achieve effective impurity removal, the problems of excessive dust concentration in grain depots and enterprises’ grain processing and cleaning sites are aimed to be solved. Field tests on the grain depots show that the average impurity content of the grain can be controlled under 0.7% after cleaning, and the dust suppression effect is as follows: dust concentration at 5 m of the operation range lower than 30 mg/m³, 15 m lower than 20 mg/m³ while 25 m lower than 10 mg/m³. Therefore, the cleaning effect and dust removal effect are better than common cleaning mechine.