The effects of transgenic Cry1Ab/Cry1Ac rice (Huahui 1) and its original parent (Minghui 63) the on the growth and development of indian meal moth during storage were studied. The results showed that, transgenic rice with Cry1Ab/Cry1Ac gene has a strong lethal effect on the youth larvae (1st to 3rd instars). Temperature has a significant effect on the development duration and speed of each stage of indian meal moth, and the development period was significantly prolonged after being fed with 2% transgenic brown rice meal. The nonlinear model of temperature-dependent developmental rate showed that the developmental threshold temperature of indian meal moth was 7.40 ℃ to 15.94 ℃, while those fed with 2% transgenic brown rice meal was 4.90 ℃ to 17.36 ℃. Our research can deepen the understanding of ecological safety of Bt transgenic rice in theory, and provide theoretical support for scientific development and utilization of Bt transgenic rice in practice.