以猪油和甲醇为原料，KOH为催化剂，采用单因素法确定醇油摩尔比、超声波功率、催化剂用量、反应温度等因素对猪油酯交换反应的脂肪酸甲酯产率的影响。单因素实验结果显示各因素的最佳值分别为醇油摩尔比6∶1，超声波功率为120 W，催化剂用量为0.8%，反应温度为60 ℃。采用响应面分析法优化超声强化KOH均相碱催化酯交换条件，结果显示最优条件为：醇油摩尔比为5.8∶1，超声功率为135.91 W，反应温度为52.78 ℃，催化剂用量为0.86%，在该条件下甲酯最大的理论转化率为99.53%。
The effects ofmolar ratio of methanol to oil, ultrasonic power, catalyst dosage and reaction temperature on the yield of fatty acid methyl ester in transesterification reaction of lardare studied by single factor method with lard and methanol as raw material, KOH as catalyst. The results show that the optimum value for all the factors are methanol/oil molar ratio 6∶1, ultrasonic power 120 W, catalyst dosage 0.8% (based on oil) and reaction temperature 60 ℃. Response surface methodology is applied to optimize homogeneous KOH-catalyzed transesterification. The results show that the optimal condition are methanol to oil ratio of 5.8∶1, ultrasonic power of 135.91 W, reaction temperature of 52.78 ℃, catalyst dosage of 0.86%, in which theoretical conversion achieve 99.53%.