The effect the ratio of wheat protein, soybean protein isolate, peanut protein, pea protein on the properties of high moisture textured wheat protein were explored by mixture design of simplex lattice, and the comprehensive evaluation of textured wheat protein was obtained by factor analysis. The regression model of the ratio of raw materials and comprehensive score was obtained, and the optimal ratio of wheat protein∶peanut protein∶pea protein = 0.655∶0.135∶0.21.