The controlled atmosphere storage with N2 is an economy and efficient technology for storing grain, so it has been increasingly concerned in various fields such as grain storage. The system and technology of the controlled atmosphere storage with N2 and the application in grain safe storage is introduced, including the applications of this technology to pest control, restraining microorganism, delaying the deterioration of grain quality and other aspects. The problems and countermeasures of the controlled atmosphere storage with N2 for constructing the digital grain depot are also analyzed, which would provide reference for broader application of this technology in the construction of digital grain depot.