The new technology that the food grade inert dust was sprayed into space and driven into the interspace of grain pile by ventilation fans is called technology of food grade inert dust aerosol control insects. The effect of the new technology was assessed by the test in grain store houses with transverse ventilation. Results showed that the aerosol phase of the inert powder can take the particles initiative to come into contact with pests of the grain heap to kill the pests. When the aerosol concentration was about 0.5 mg/kg, many kinds of pests in the grain store houses, especially Cryptolestes pusillus, were effectively killed.