Abstract:A fast method was developed for the determination of 5 organophosphorus pesticide residues (dimethoate, chlorpyrifos, malathion, isocarbophos, fenitrothion) in paddy by neutral alumina dispersive solid phase extraction - gas chromatography with flame photometric detector (DSPE-GC-FPD). The powdered samples were extracted with acetonitrile. The extract was purified by neutral alumina DSPE,dried by nitrogen evaporator with water bath at 70 ℃,and dissolved by acetone and determined by capillary gas chromatograph with flame photometric detector(CGC-FPD). The results showed that the 5 organophosphorus pesticide showed a good linear relationship in the range of 0.05~5.00 μg/mL, all of their linear correlation coefficients were 0.999 9, the limit of detection was 0.002 mg/kg, and the minimum quantitative limit was 0.007 mg/kg. The spiked recoveries at three levels of standard additions in paddy were between 97.7%~108.0%, and the RSDs (n=6) were between 0.8%~5.7%. This method could be used to determine 5 organophosphorus pesticide residues in paddy at the same time.