Deoxynivalenol and zearalenone are the main two mycotoxins occurred in wheat infected by scab.Some factors,including generating conditions，physicochemical property，toxicological effects,hazardous formation and distribution range of the two mycotoxins,as well as the changes of the two toxins content during wheat processing,such as wheat cleaning,grinding,baking and cooking,were summarized，in order to make further inquiry on the change of the two main mycotoxins in the production of wheat products.