An effective method was developed for rapid determination of five trace elements in wheat flour by microwave digestion-high resolution continuum source graphite furnace atomic absorption spectrophotometry. Under the selected work conditions, the contents of Cu, Cd, Pb, Mn, Al in wheat flour were 1.35, 0.099,0.039,5.01,10.2 μg/g, and the detection limits were 1.22,0.077,1.53,0.614,1.54 ng/mL, respectively. The recoveries for the samples were 96.0%～104.7%, and the precision relative standard deviations were less than 5.81%.