Research Status of Embryonic Developmental Toxicity and Biological Monitoring of Exposure to Traditional and Emerging Mycotoxins during Pregnancy
HAN Xiao-min1, YE Jin2, JI Jian3, XU Wen-jing1, WU Yu2, YE Yong-li3,
Rudolf KRSKA4,5, SUN Xiu-lan3, BAI Li1*
(1. China National Center For Food Safety Risk Assessment, Beijing 100022, China;
2. Institute of Grain and Oil Quality and Safety, Academy of National Food and Strategic Reserves Administration, Beijing 100037, China;
3. School of Food Science and Technology, Jianagnan University, Wuxi, Jiangsu 214122, China;
4. Institute of Bioanalytics and Agro-Metabolomics, Department of Agrobiotechnology (IFA Tulln), University of Natural Resources and Life Sciences, Vienna (BOKU), 3430 Tulln, Austria;
5. Institute for Global Food Security, School of Biological Sciences, Queen’s University Belfast, Belfast BT9 5DL, Northern Ireland, UK)
Abstract: Mycotoxins are toxic secondary metabolites produced by certain fungal species under specific conditions. Research has found that exposure to various fungal toxins can cause embryonic developmental toxicity, such as embryo arrest, abortion, and intrauterine fetal developmental delay. There are no systematic reports on the impact of exposure to fungal toxins during pregnancy on the toxicity of intrauterine fetal development and biological monitoring. Therefore, in order to prevent and reduce the harm of fungal toxins during pregnancy, this paper summarizes the research status of embryonic developmental toxicity, as well as the research status of biological monitoring technologies based on biomarkers such as exposure biomarkers and biomakers of effect, which are caused by traditional fungal toxins such as aflatoxin, deoxynivalenol, zearalenone, and emerging fungal toxins such as Alternaria toxins, beauverin, and enniatins. The aim of the paper is for construction of the healthy China.
Key words: pregnancy; traditional and emerging mycotoxin; embryo developmental toxicity; biological monitoring
Chinese Library Classification Number: TS201.6
Documentary Identification Code: A Article ID: 1007-7561(2024)04-0016-08
Published time on CNKI: 2024-06-29 13:25:45
Published address on CNKI: https://link.cnki.net/urlid/11.3863.TS.20240628.1443.005
