Under the guidance of the principle of integrated control, this paper investigated and sorted out several methods of integrated control of stored grain pests (physical, chemical and biological control), the management principles of phosphine resistance, the effect of resistance control, essentials and existing problems of comprehensive prevention and control. Some suggestions on the development of integrated pest control technology in stored grain were put forward. In order to deal with pest resistance effectively, reduce pest occurrence, reduce the use of chemicals and the dependence on chemical fumigations, we should pay attention to the combined application of fumigation, protectant, physical control and biological control methods to improve the integrated pest control technology system for grain post-harvest storage and logistics that is suitable for China, so as to comply with the concept of “green, ecological, economic and efficient” and provide ideas for scientific and technological development of integrated pest control in grain storage in China.