The effect of peanut moisture, protein, fatty acid, resveratrol and vitamin E on the degradation of AFB1 treated by atmospheric pressure plasma was explored. The results showed that the degradation rate of AFB1 reached to 62.5% in pure acetonitrile system by plasma of 170V for 100s. Then after adding 6% water , 25% peanut protein, 4mg/100g resveratrol, 40mg/100g vitamin E, fatty acid(oleic acid, linoleic acid and palmitic acid) and multicomponent mixtures, the degradation rate of AFB1 were 72.25%, 51.6%, 60.12%,52.63%,58.3% and 51.08%, respectively. Compared with the pure acetonitrile system, the degradation rate of AFB1 increased by 9.75% after adding water, while the degradation rates of AFB1 decreased after adding other components. Therefore peanut components have effect on the degradation rate of AFB1, and have a guiding role in practical application.