International Commission on Microbiological Specification for Foods (ICMSF) proposed the establishment of Food Safety Objective (FSO) and the formula. Through the establishment of microbial Performance Objective (PO) and Food Safety Objective (FSO) with FSO formula, it is expected to explain how to collect and analysis the data information to reduce the microbial level H0 & ΣR and increase the microbial level ΣI, to find the key elements and key values of product microbial control, to provide strong data support for the specific execution of GMP and HACCP was provided, which could ensure the product qualification ratio is 100%.